Colloid MCC High quality excited price from ACTA
1. Introduction to Colloidal Microcrystalline Cellulose (colloid MCC)
Colloidal microcrystalline cellulose (colloid MCC) is a versatile composite excipient widely used across industries. Composed of 80-90% microcrystalline cellulose (MCC) and 10-20% sodium carboxymethyl cellulose (CMC-Na), it forms a stable colloidal suspension or free-flowing powder. This unique combination enhances dispersibility, viscosity, and stability compared to pure MCC, making it indispensable in food, pharmaceutical, and industrial applications.
Key Properties:
- Chemical Composition: MCC (C₆H₁₀O₅)ₙ + CMC-Na
- Appearance: White to off-white powder/colloidal suspension
- pH: 5.5–7.5 (neutral to slightly acidic)
- Solubility: Forms stable colloidal dispersions in water
2. Functional Properties and Applications of colloid MCC
Colloidal MCC’s unique properties drive its adoption in diverse sectors. Let’s explore how it adds value in each industry:
| Industry | Application Examples | Functional Role |
|---|---|---|
| Food | Dairy products, sauces, bakery, beverages | Thickener, stabilizer, fat replacer |
| Pharma | Tablets, capsules, controlled-release matrices | Binder, disintegrant, viscosity regulator |
| Cosmetics | Creams, lotions, gels | Rheology modifier, texture enhancer |
| Industrial | Paints, coatings, inks | Suspension aid, viscosity controller |
Why It Works:
- Suspension Stability: CMC-Na prevents sedimentation in beverages. For example, ACTA-tested neutral cocoa milk showed 98% sedimentation prevention over six months.
- Thermal Stability: Maintains viscosity at high temperatures. Sauces retain 92% viscosity after 30 minutes at 140°C.
- Biocompatibility: Non-toxic and inert, with no enzymatic digestion in the human gut.
3. Qingdao ACTA Biotechnology Co., Ltd. – Industry Leader
Qingdao ACTA Biotechnology is China’s premier manufacturer of pharmaceutical- and food-grade colloidal MCC. Their products meet or exceed USP, EP, JP, and CP standards, backed by rigorous quality control.
3.1 Product Grades and Specifications of colloid MCC
ACTA offers tailored grades for specific applications. Below are the key specifications:
| TEST ITEMS | ACT591 | ACT3212 | ACT611 | ACT538 | ACT521 |
| Loss on drying,w/% | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 |
| Residue on ignition,w/% | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 |
| Viscosity,1.2%,mpa.s | 39-91 | 50-200 | 50-151 | 39-175 | 50-100 |
| Particle Size retained on 60 mesh sieve | <1 | <1 | <1 | <1 | <1 |
| Heavy Metal,mg/kg | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 |
| Total aerobic microbial count,cfu/g | ≤1000 | ≤1000 | ≤1000 | ≤1000 | ≤1000 |
| Total moulds and yeasts count，cfu/g | ≤100 | ≤100 | ≤100 | ≤100 | ≤100 |
| Escherichia coli | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Salmonella species | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Staphylococcus aureus | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Pseudomonas aeruginosa | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Application | food and beverage | Milk shake, sauce | food and beverage | Neutral milk drinks, vegetable protein drinks | food and beverage |
2. Specifications of colloid MCC
| TEST ITEMS | ACT509 | ACT600 | ACT610 | ACT428 | ACT631 | ACT651 |
| Loss on drying,w/% | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 |
| Residue on ignition,w/% | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 |
| Viscosity,1.2%,mpa.s | 60-150 | 2000-8000(2.6%） | 1200-2000 | 130-230 | 2000-8000（2.6%） | 50-151（2.6%） |
| Particle Size retained on 60 mesh sieve | <1 | <1 | <1 | <1 | <1 | <1 |
| Heavy Metal,mg/kg | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 |
| Total aerobic microbial count,cfu/g | ≤1000 | ≤1000 | ≤1000 | ≤1000 | ≤1000 | ≤1000 |
| Total moulds and yeasts count，cfu/g | ≤100 | ≤100 | ≤100 | ≤100 | ≤100 | ≤100 |
| Escherichia coli | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Salmonella species | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Staphylococcus aureus | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Pseudomonas aeruginosa | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Application | Neutral milk drinks, vegetable protein drinks | Milk shake, sauce | Bakery,sauce | Neutral milk drinks, vegetable protein drinks | food and beverage | food and beverage |
3.
| TEST ITEMS | ACT440 | ACT450 | ACT480 | ACT996 | ACT981 | ACT8329 |
| Loss on drying,w/% | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 | ≤7.0 |
| Residue on ignition,w/% | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 | ≤5.0 |
| Viscosity,1.2%,mpa.s | 200-400 | 400-700 | 700-900 | 3000-5500(2.6%) | 2000-3500（2.6%） | 1000-1600（2.6%） |
| Particle Size retained on 60 mesh sieve | <1 | <1 | <1 | <1 | <1 | <1 |
| Heavy Metal,mg/kg | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 | ≤10 |
| Total aerobic microbial count,cfu/g | ≤1000 | ≤1000 | ≤1000 | ≤1000 | ≤1000 | ≤1000 |
| Total moulds and yeasts count，cfu/g | ≤100 | ≤100 | ≤100 | ≤100 | ≤100 | ≤100 |
| Escherichia coli | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Salmonella species | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Staphylococcus aureus | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Pseudomonas aeruginosa | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g | Not detected/10g |
| Application | Paint and printing materials | Paint and printing materials | Bakery,sauce | food and beverage | food and beverage | food and beverage |
Extended Range:
- ACT600: 2,000–8,000 mPa·s (ideal for high-viscosity milkshakes).
- ACT428: 130–230 mPa·s (perfect for neutral milk drinks).
3.2 Quality Control and Testing
ACTA employs advanced analytical methods to ensure product consistency:
| Test Parameter | Method | Standard |
|---|---|---|
| Viscosity | Brookfield viscometer (25°C) | Grade-specific ranges |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | ≤10 mg/kg total |
| Microbial Safety | Plate count methods | Pathogen-free certification |
4. Regulatory Compliance and Safety
ACTA’s colloidal MCC is globally approved, ensuring safety and compliance:
- Pharmacopeial Standards: USP 43-NF 38, EP 10.0, JP 17, CP 2020.
- Food Safety: EFSA E460(i), US FDA GRAS.
- Toxicity: Non-toxic, non-irritant, non-carcinogenic.
Strict Limits:
- Heavy metals (Pb, Cd, Hg, As): <10 ppm.
- Microbial contamination: No pathogens detected.
5. Market Data and Pricing of colloid MCC
ACTA offers competitive pricing without compromising quality:
| Source/Brand | Viscosity Range (mPa·s) | Price (USD/kg) | Notes |
|---|---|---|---|
| Qingdao ACTA | 39–2,000+ | 1.2–2.5 | Premium pharma/food grade |
| Roquette TABULOSE® SC 591 | 39–91 | 1.5–2.0 | Global benchmark |
| Sigma-Aldrich | Variable | 3.0–5.0 | Research-grade |
6. Technical Advantages of Qingdao ACTA MCC
- Superior Suspension: Optimized CMC-Na content prevents sedimentation.
- Batch Consistency: Advanced manufacturing ensures reproducibility.
- Technical Support: Custom formulation assistance available.
7. Recommendation
Qingdao ACTA Biotechnology’s colloidal MCC is ideal for:
- Dairy Beverages: Stable suspension and creamy texture.
- Pharmaceutical Tablets: Controlled release and mechanical strength.
- Food Sauces: Viscosity control and texture enhancement.
In the specialized field of colloidal microcrystalline cellulose (CMC), Qingdao ACTA Biotechnology Co., Ltd. has emerged as a global industry leader through its technical expertise, uncompromising product quality, and strategic market vision. Since its establishment in 2002, the company has focused on research, development, and production of pharmaceutical-grade CMC, addressing the critical needs of domestic and international markets while redefining “Made in China” excellence in global biotechnology.
Technological Leadership: Redefining Industry Benchmarks
Qingdao ACTA Biotechnology understands that sustained technological innovation forms the cornerstone of competitiveness in the CMC sector. The company has continuously invested in R&D, imported advanced production equipment, and established a comprehensive system encompassing research, manufacturing, and quality control. Its CMC products exceed pharmacopoeia standards from Europe, the United States, and Japan across multiple critical performance indicators:
- Unmatched Gel Strength: Through proprietary production processes, ACTA’s CMC demonstrates superior suspension capabilities, enhancing product stability in complex formulations and ensuring consistent end-user experience.
- Optimized Colloid Purity: With higher active ingredient content compared to domestic and international counterparts, ACTA’s CMC delivers superior functional performance at equivalent usage levels.
- Broad Viscosity Spectrum: The company’s technical platform supports full-spectrum product development with viscosity ranges spanning 39–8,000 mPa·s, catering to diverse requirements across food, pharmaceutical, cosmetic, and industrial applications.
- Rigorous Microbial Control: ACTA maintains stringent quality protocols, ensuring microbial counts for molds and yeasts remain well below both domestic and global standards—a critical safeguard for food safety.
Proven Application Performance
ACTA’s CMC products excel across multiple application domains:
- Food Sector: In neutral cocoa milk formulations, ACTA’s CMC achieves 98% sedimentation prevention over 6-month storage periods, maintaining product homogeneity and consumer appeal.
- Acidic Beverages: Tailored CMC variants resist phase separation in low-pH environments, preserving clarity and texture in acidic fruit juices.
Smart Manufacturing: Ensuring Quality and Efficiency
To continually enhance product quality and operational efficiency, ACTA has implemented a state-of-the-art smart manufacturing system:
- Advanced Production Infrastructure: With an annual capacity of 3,000 metric tons, the facility incorporates 5 independent HVAC systems and 18 industrial-grade air purifiers, maintaining cleanroom conditions compliant with solid pharmaceutical preparation standards.
- Intelligent Production Workflow: Fully automated equipment enables end-to-end process control from raw material input to finished product packaging, maximizing efficiency while ensuring consistent quality.
- Comprehensive Quality Assurance: The company operates a rigorous quality management system equipped with atomic absorption spectrometers, UV-Vis spectrophotometers, TOC analyzers, and HPLC systems. Every batch undergoes meticulous testing to meet stringent internal specifications and customer requirements.
Customer-Centric Innovation
Qingdao ACTA prioritizes customer success through:
- Customized Solutions: Tailored product development addresses specific technical challenges in R&D and production processes.
- Expert Technical Support: A dedicated team provides end-to-end assistance covering product selection, application development, and after-sales service.
- Reliable Supply Chain: Robust production capacity and efficient logistics guarantee timely order fulfillment.
8. Contact Qingdao ACTA Biotechnology
For samples, technical datasheets, or formulation support:
- Email: [email protected]
- Phone: +86-18263653583
- Website:www.actabiotechnology.com
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