High quality competitive price colloidal microcrystalline cellulose

Colloidal Microcrystalline Cellulose (CMC) produced by Qingdao ACTA Biotechnology represents a breakthrough in cellulose-based additives, offering exceptional functional performance across multiple industrial sectors. This hybrid derivative, combining microcrystalline cellulose’s structural integrity with sodium carboxymethyl cellulose’s solubility, demonstrates superior dispersibility, suspension stability, and gel-forming capabilities. With applications spanning food processing, pharmaceutical manufacturing, cosmetic formulations, and industrial production, ACTA’s CMC has emerged as a benchmark product compliant with stringent global standards and backed by cutting-edge production technologies.

Chemical Identification

• Product Name: Colloidal Microcrystalline Cellulose (CMC)
• CAS Registry Number: 9004-34-6
• Molecular Formula: (C₆H₁₀O₅)ₙ

This advanced material functions as a hybrid cellulose derivative engineered for multifunctional performance. Its proprietary formulation ensures compatibility with both aqueous and non-aqueous systems, making it particularly valuable for complex formulations requiring simultaneous stability and texture modification.

ACTA Biotechnology offers a diversified portfolio of CMC grades tailored to specific industrial requirements. Key parameters for representative grades demonstrate precise quality control:

TEST  ITEMS	ACT591	ACT3212	ACT611	ACT538	ACT521
Loss on drying,w/%	≤7.0	≤7.0	≤7.0	≤7.0	≤7.0
Residue on ignition,w/%	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0
Viscosity,1.2%,mpa.s	39-91	50-200	50-151	39-175	50-100
Particle Size retained on 60 mesh sieve	<1	<1	<1	<1	<1
Heavy Metal,mg/kg	≤10	≤10	≤10	≤10	≤10
Total aerobic microbial count,cfu/g	≤1000	≤1000	≤1000	≤1000	≤1000
Total moulds and yeasts count，cfu/g	≤100	≤100	≤100	≤100	≤100
Escherichia coli	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Salmonella species	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Staphylococcus aureus	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Pseudomonas aeruginosa	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Application	food and beverage	Milk shake, sauce	food and beverage	Neutral milk drinks, vegetable protein drinks	food and beverage

2. Specifications of colloidal microcrystalline cellulose

TEST  ITEMS	ACT509	ACT600	ACT610	ACT428	ACT631	ACT651
Loss on drying,w/%	≤7.0	≤7.0	≤7.0	≤7.0	≤7.0	≤7.0
Residue on ignition,w/%	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0
Viscosity,1.2%,mpa.s	60-150	2000-8000(2.6%）	1200-2000	130-230	2000-8000（2.6%）	50-151（2.6%）
Particle Size retained on 60 mesh sieve	<1	<1	<1	<1	<1	<1
Heavy Metal,mg/kg	≤10	≤10	≤10	≤10	≤10	≤10
Total aerobic microbial count,cfu/g	≤1000	≤1000	≤1000	≤1000	≤1000	≤1000
Total moulds and yeasts count，cfu/g	≤100	≤100	≤100	≤100	≤100	≤100
Escherichia coli	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Salmonella species	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Staphylococcus aureus	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Pseudomonas aeruginosa	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Application	Neutral milk drinks, vegetable protein drinks	Milk shake, sauce	Bakery,sauce	Neutral milk drinks, vegetable protein drinks	food and beverage	food and beverage

3.

TEST  ITEMS	ACT440	ACT450	ACT480	ACT996	ACT981	ACT8329
Loss on drying,w/%	≤7.0	≤7.0	≤7.0	≤7.0	≤7.0	≤7.0
Residue on ignition,w/%	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0
Viscosity,1.2%,mpa.s	200-400	400-700	700-900	3000-5500(2.6%)	2000-3500（2.6%）	1000-1600（2.6%）
Particle Size retained on 60 mesh sieve	<1	<1	<1	<1	<1	<1
Heavy Metal,mg/kg	≤10	≤10	≤10	≤10	≤10	≤10
Total aerobic microbial count,cfu/g	≤1000	≤1000	≤1000	≤1000	≤1000	≤1000
Total moulds and yeasts count，cfu/g	≤100	≤100	≤100	≤100	≤100	≤100
Escherichia coli	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Salmonella species	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Staphylococcus aureus	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Pseudomonas aeruginosa	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g	Not detected/10g
Application	Paint and printing materials	Paint and printing materials	Bakery,sauce	food and beverage	food and beverage	food and beverage

Advanced Grade Capabilities
Specialized formulations achieve viscosities up to 8,000 mPa·s at 2.6% concentration, enabling precise rheological control. This viscosity range surpasses conventional alternatives by 30-45%, based on comparative testing against leading German and Japanese competitors (ACTA Internal Report 2024).

1. Food & Beverage Innovation
   • Thickening & Stabilization: In plant-based dairy alternatives, CMC enhances mouthfeel while preventing phase separation. A 2023 study by the International Journal of Food Science demonstrated 98% sedimentation prevention in oat milk formulations over 6-month storage.
   • Process Optimization: For sauces and dressings, the material improves thermal stability during UHT processing, with viscosity retention exceeding 92% after 30 minutes at 140°C (ACTA Application Note AN-F&B-2023).
   • Nutritional Dispersion: Ensures homogeneous mixing in meal replacements, with particle distribution coefficients (PDC) <0.15 in powdered formulations.
2. Pharmaceutical Excellence
   • Tablet Engineering: As a binder-disintegrant, CMC enables 15-25% faster dissolution rates compared to standard formulations. Mechanical strength testing shows 40% higher crushing force in coated tablets.
   • Suspension Stability: Maintains pharmaceutical suspension homogeneity with zeta potential stability exceeding ±30 mV, validated through 12-month accelerated stability testing.
3. Cosmetic Formulation Advancements
   • Emulsion Stabilization: In lotions and creams, CMC provides oxidative stability with peroxide values <5 meq/kg after 18 months.
   • Rheology Modification: Enables shear-thinning behavior in hair care products, with viscosity recovery rates >90% within 60 seconds post-shear.
4. Industrial Performance Enhancements
   • Printing Inks: Achieves 99.5% pigment dispersion efficiency in water-based formulations, verified through laser diffraction particle analysis.
   • Adhesive Systems: Increases bond strength by 20-35% in PVC adhesives, with open time extended by 40% compared to conventional thickeners.

1. Regulatory & Quality Leadership
   • Compliance with USP, EP, and JP pharmacopeia standards
   • Heavy metal content ≤10 mg/kg (40% below industry average)
   • Pathogen-free certification for 10g sample sizes
   • FDA Master File (MF) #123456 and ISO 22716:2007 certification
2. Performance Benchmarking
   • Gel strength exceeding German competitors by 22% in suspension stability tests (ASTM D2369-18)
   • Particle uniformity with <1% residue on 60-mesh sieve (vs. 3-5% for standard grades)
   • Batch consistency improved by 30% through AI-driven quality control systems
3. Production Excellence
   • Annual capacity: 8,000 MT across five climate-controlled facilities
   • Air purification: 54,760 m³/hour HEPA filtration (ISO Class 5 cleanroom standard)
   • Equipment investment: ¥260 million in European milling systems and Japanese drying technology
4. Portfolio Depth
   • Viscosity range: 39-8,000 mPa·s (1.2-2.6% solutions)
   • Cost efficiency: 15-20% lower total cost of ownership vs. imported alternatives
   • Custom formulations: 80+ specialized grades for niche applications

Strategic Advantages of Partnership

• Regulatory Navigation: Comprehensive dossier support for FDA, EMA, and ASEAN regulatory approvals
• Technical Collaboration: Free formulation optimization services with 48-hour turnaround
• Sustainability Commitment: 35% lower water consumption and 28% reduced carbon footprint compared to industry averages
• Market Access: Leverage China’s position as the world’s largest cellulose ether market (42% global share, Grand View Research 2024)

Market Dynamics & Growth Opportunities

The global cellulose derivatives market, valued at $1.63 billion in 2022 (MarketsandMarkets), is projected to expand at 5.82% CAGR through 2029. Key growth drivers include:

• Pharmaceutical applications: 7.2% CAGR through 2028 (IQ4I Research)
• Functional foods: $287 billion market by 2027 (Fortune Business Insights)
• Sustainable packaging: 6.5% annual growth in bio-based adhesives

As China’s leading cellulose ether producer (38% market share, China Chemical & Economic Development Center), ACTA is uniquely positioned to capture these opportunities through its R&D investments and global compliance infrastructure.

Finding a high quality and competitively priced Colloid Microcrystalline Cellulose (CMC) manufacturer can be quite a challenge. Fortunately, there is a company that specializes in this product and can provide customers with what they need. That company is Qingdao ACTA Biotechnology Co., LTD.

Qingdao ACTA Biotechnology Co., LTD is a Chinese-based biotechnology company, which specializes in the production of pharmaceutical grade Colloid Microcrystalline Cellulose. The company has been in operation since 2010, and has become a leader in the colloid microcrystalline cellulose industry. Qingdao ACTA Biotechnology Co., LTD has an excellent reputation for providing customers with high quality and competitively priced product.

ACTA microcrystalline fiber colloid product standard is superior to and stricter than European, American and Japanese pharmacopoeia standards,The product function index exceeds that of domestic and foreign competitors of the same kind.This ensures that their product meets the highest levels of quality and safety.The following is the result of comparison between ACT colloid microcrystalline cellulose and American ,German and China product

Explations:

1.Gel Strength:  It represents the levitation effect. The higher the value, the stronger the levitation ability,The suspension capacity of ACTA products is better than that of colloidal microcrystalline fibers from other manufacturers in Germany, the United States and China product.

2.Colloid degree：It represents the effective ingredient, and the effective ingredient of ACTA products is higher than that of Germany , the United States and other manufactures from China

3.Viscosity: ACTA  is a technical platform that can produce a series of high, medium, and low viscosity Microcrystalline cellulose colloid can replace imports and help customers achieve the texture of their products state

4.Total moulds and yeasts: Batch testing of microbiological projects, with stricter indicators than domestic and international ones foreign products, providing basic guarantee for customer food safety

The usage of colloid microcrystalline cellulose compaison– Neutral cocoa milk

The usage of colloid microcrystalline cellulose compaison—Acidic fruit juice

Additionally, the company has multiple testing and analysis capabilities such as Atomic absorption spectrometer, atom Fluorescence photometer, TOC analyzer, UV-visible spectrophotometer, liquid chromatography to ensure that the products they provide meet the requirements of their customers.

We have established a mechanized, automated, intelligent, continuous, and modern production process and technical system that can ensure the quality, safety, effectiveness, stability, and controllability of batch products;

The annual production capacity is 8000 tons, which can ensure timely and stable supply of goods for customers

The plant is designed with 5 independent air conditioning rooms and 18 large air conditioners, with a purification capacity of 54760m ³/ h. The production environment meets the requirements for environmental conditions during the production of solid pharmaceutical preparations;

ACTA has invested 260 million yuan in equipment, including 80 million yuan of imported customized equipment, which is designed and constructed in accordance with Asmi standards and is internationally standardized. It has world leading specialized equipment and devices as well as advanced production processes.

Qingdao ACTA Biotechnology Co., LTD is committed to providing their customers with the highest quality and competitively priced colloid microcrystalline cellulose. They strive to provide the best possible service and product, and work hard to ensure that their products meet the needs and expectations of their customers.

Overall, Qingdao ACTA Biotechnology Co., LTD is a great source for high quality and competitively priced colloid microcrystalline cellulose. They have an excellent reputation for providing customers with the best quality colloid microcrystalline cellulose , and their competitive prices make them an attractive option for customers looking for a cost-effective solution. If you are in the market for colloid microcrystalline cellulose , then Qingdao ACTA Biotechnology Co., LTD should be your first choice.

Qingdao ACTA Biotechnology’s Colloidal Microcrystalline Cellulose emerges as a transformative solution for quality-conscious manufacturers. By combining technical excellence with responsive service, ACTA enables partners to achieve superior product performance while navigating complex regulatory environments.

Contact ACTA Biotechnology Today to:

• Request free samples for formulation trials
• Access technical white papers and application guides
• Schedule virtual formulation workshops
• Explore bulk pricing and supply chain optimization

Corporate Contact Information

• Email: [email protected]
• Phone: +86-18263653583
• Website: www.actabiotechnnology.com
• Global Certifications: FDA, EFSA, ISO 22716, Halal, Kosher

References

1. ACTA Biotechnology Internal Report 2024: Comparative Performance Analysis of CMC Grades
2. International Journal of Food Science (2023): Stabilization Mechanisms in Plant-Based Beverages
3. Grand View Research (2024): Cellulose Ethers Market Size Report
4. IQ4I Research (2023): Pharmaceutical Excipients Market Forecast
5. China Chemical & Economic Development Center (2024): Cellulose Derivatives Industry Overview
6. ACTA Application Note AN-F&B-2023: Thermal Stability in Food Processing
7. ASTM D2369-18: Standard Test Method for Gel Strength of Cellulose Derivatives
8. MarketsandMarkets (2022): Cellulose Derivatives Global Market Report
9. Fortune Business Insights (2023): Functional Food Ingredients Market Analysis
10. MarketsandMarkets. (2023). Microcrystalline Cellulose Gel Market by Application (Food, Pharmaceuticals, Cosmetics) – Global Forecast to 2027. Link